Investigation of Gene Expression of MMP-2 and TIMP-2 mRNA in Rat Lung in Inhaled Nickel Oxide and Titanium Dioxide Nanoparticles.
Authors: Y. Morimoto, T. Oyabu, A. Ogami, T. Myojo, E. Kuroda, M. Hirohashi, M. Shimada, W. Lenggoro, K. Okuyama and I. Tanaka

(An experimental study, with School of Medicine – University of Occupational and Environmental Health, and Graduate School of Engineering – Hiroshima University)

Industrial Health, 2011. >> PubMed >> PDF.

4週間（毎日6時間運転）でラットに数十nm～数百nmの酸化物粒子を吸入させ、ラット肺における遺伝子発現に関する研究。共同研究：産業医科大学と広島大学大学院工学研究科. Project funded by NEDO (AIST site).